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Journal article

The genetics of FAP and FAP-like syndromes.

Abstract:

The presence of multiple adenomatous polyps in the large bowel confers a high lifetime risk of colorectal cancer. Although many cases of classical familial adenomatous polyposis (> 100 polyps) can be accounted for by mutations in the adenomatous polyposis coli (APC) gene, a large group of patients remains with multiple (5-100) adenomas and in whom there is no detectable APC mutation. Recently two new genetic variants have been found to be associated with multiple colorectal adenomas and ca...

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Publication status:
Published

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Publisher copy:
10.1007/s10689-005-5673-3

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Familial cancer
Volume:
5
Issue:
3
Pages:
221-226
Publication date:
2006
DOI:
EISSN:
1573-7292
ISSN:
1389-9600
URN:
uuid:3b51bd8a-e60c-4bdc-bd03-376018588256
Source identifiers:
72053
Local pid:
pubs:72053

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