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Correlation of cavitation with ultrasound enhancement of thrombolysis.

Abstract:

Pulsed ultrasound, when used as an adjuvant to recombinant tissue plasminogen activator (rt-PA), has been shown to enhance thrombolysis in the laboratory as well as in clinical trials for the treatment of ischemic stroke. The exact mechanism of this enhancement has not yet been elucidated. In this work, stable and inertial cavitation (SC and IC) are investigated as possible mechanisms for this enhancement. A passive cavitation detection scheme was utilized to measure cavitation thresholds at ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
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Journal:
Ultrasound in medicine and biology
Volume:
32
Issue:
8
Pages:
1257-1267
Publication date:
2006-08-05
DOI:
EISSN:
1879-291X
ISSN:
0301-5629
URN:
uuid:3b4ce952-3cf9-4266-ab84-3b3a3194c6e9
Source identifiers:
62513
Local pid:
pubs:62513

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