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Deep brain stimulation abolishes slowing of reactions to unlikely stimuli

Abstract:

The cortico–basal–ganglia circuit plays a critical role in decision making on the basis of probabilistic information. Computational models have suggested how this circuit could compute the probabilities of actions being appropriate according to Bayes' theorem. These models predict that the subthalamic nucleus (STN) provides feedback that normalizes the neural representation of probabilities, such that if the probability of one action increases, the probabilities of all other available actions...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1523/JNEUROSCI.1065-14.2014

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Oxford college:
Brasenose College
ORCID:
0000-0002-1192-3834
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Oxford college:
All Souls College
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Oxford college:
Brasenose, Brasenose College
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
ORCID:
0000-0001-5980-9830
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Oxford college:
Exeter, Exeter College
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Publisher:
Society for Neuroscience Publisher's website
Journal:
Journal of Neuroscience Journal website
Volume:
34
Issue:
33
Pages:
10844-10852
Publication date:
2014-08-13
Acceptance date:
2014-06-24
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Pubs id:
pubs:480092
URN:
uri:3b4ce380-3921-4837-8f28-54463f27c0a9
UUID:
uuid:3b4ce380-3921-4837-8f28-54463f27c0a9
Local pid:
pubs:480092

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