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Journal article

Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes

Abstract:: Because enriched environment (EE) and exercise increase and aging decreases immune response, we hypothesized that environmental enrichment and aging will, respectively, delay and increase prion disease progression. Mice dorsal striatum received bilateral stereotaxic intracerebral injections of normal or ME7 prion infected mouse brain homogenates. After behavior analysis, animals were euthanized and their brains processed for astrocyte GFAP immunolabeling. Our analysis related to the environme...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Bento-Torres, J., Sobral, L., Reis, R., De Oliveira, R., Anthony, D., Vasconcelos, P., & Picanço Diniz, C. (2017). Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes. Oxidative Medicine and Cellular Longevity, 2017.

MLA Style

Bento-Torres, J., et al. “Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.” Oxidative Medicine and Cellular Longevity, vol. 2017, Hindawi Publishing Corporation, 2017.

Chicago Style

Bento-Torres, J, L Sobral, R Reis, R De Oliveira, D Anthony, P Vasconcelos, and C Picanço Diniz. 2017. “Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.” Oxidative Medicine and Cellular Longevity 2017.
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Files:: 4504925.pdf

(Version of record, pdf, 5.4MB)

Publisher copy:: 10.1155/2017/4504925

Authors

+ Bento-Torres, J More by this author

Role:

Author

+ Sobral, L More by this author

Role:

Author

+ Reis, R More by this author

Role:

Author

+ De Oliveira, R More by this author

Role:

Author

+ Anthony, D More by this author

Institution:

University of Oxford

Oxford college:

Somerville College

Role:

Author

More authors...

Funding

+ Universidade Federal do Para More from this funder

Grant:

Edital PROPESP/FADESP, PIAPA 2015

+ Coordenação de Aperfeiçoamento de Pessoal de Nível Superior More from this funder

Grant:

99999.001533/2014-02

+ Conselho Nacional de Pesquisa More from this funder

Grant:

300203/2010-1

471077/2007-0

Bibliographic Details

Publisher:: Hindawi Publishing Corporation Publisher's website
Journal:: Oxidative Medicine and Cellular Longevity Journal website
Volume:: 2017
Publication date:: 2017-01-24
Acceptance date:: 2016-11-24
DOI:: 10.1155/2017/4504925
EISSN:: 1942-0994
ISSN:: 1942-0900

Item Description

Keywords:: Journal Article
Pubs id:: pubs:680842
UUID:: uuid:3b4a49fd-6770-4630-a797-216542008e4f
Local pid:: pubs:680842
Source identifiers:: 680842
Deposit date:: 2017-02-26

Terms of use

Copyright holder:: Bento-Torres et al
Copyright date:: 2017
Notes:: Copyright © 2017 J. Bento-Torres et al. This is an open access article distributed under the Creative Commons Attribution License.

Licence:: CC Attribution (CC BY)

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