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Journal article

Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.

Abstract:

Purpose
Our aim was to determine the role of end-of-induction (EOI) minimal residual disease (MRD) assessment in the identification and stratification of induction failure in patients with pediatric acute lymphoblastic leukemia (ALL) and to identify genetic abnormalities that drive disease in these patients.

Patients and Methods
Analysis included 3,113 patients who were treated in the Medical Research Council UKALL2003 multicenter randomized trial (NCT0...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1200/JCO.2016.69.6278

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Publisher:
American Society of Clinical Oncology Publisher's website
Journal:
Journal of Clinical Oncology Journal website
Volume:
35
Issue:
6
Pages:
660-667
Publication date:
2017-01-03
Acceptance date:
2016-10-25
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
Source identifiers:
671005
Language:
English
Keywords:
Pubs id:
pubs:671005
UUID:
uuid:3b3b91b3-e851-4ddb-badf-8b8379bb6a5e
Local pid:
pubs:671005
Deposit date:
2017-02-09

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