Multicenter evaluation of neurofilaments in early symptomatic amyotrophic lateral sclerosis
Objective: To examine Nf concentrations according to symptom onset and clinical diagnostic certainty categories of ALS.
Methods: We measured Nf light chain (NfL) and phosphorylated Nf heavy chain (pNfH) CSF and NfL serum levels in ALS patients with first symptom onset ≤6 months (n=48), >6 months (n=128) from sampling, patients with other neurological diseases, differential diagnoses of a motor neuron disease (MND mimics) and other MND variants to...Expand abstract
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- Peer reviewed
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- American Academy of Neurology
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- Copyright © 2017 American Academy of Neurology.
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