Journal article
Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.
- Abstract:
-
Epigenetic processes play a key role in the central nervous system and altered levels of 5-methylcytosine have been associated with a number of neurologic phenotypes, including Alzheimer's disease (AD). Recently, 3 additional cytosine modifications have been identified (5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine), which are thought to be intermediate steps in the demethylation of 5-methylcytosine to unmodified cytosine. Little is known about the frequency of these modif...
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- Publisher copy:
- 10.1016/j.neurobiolaging.2014.02.002
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Bibliographic Details
- Journal:
- Neurobiology of aging
- Volume:
- 35
- Issue:
- 8
- Pages:
- 1850-1854
- Publication date:
- 2014-08-01
- DOI:
- EISSN:
-
1558-1497
- ISSN:
-
0197-4580
- Source identifiers:
-
460562
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:460562
- UUID:
-
uuid:3af9728b-a3e0-4693-b1e2-f29670ed2006
- Local pid:
- pubs:460562
- Deposit date:
- 2014-06-16
Terms of use
- Copyright date:
- 2014
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