- Abstract:
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Background. There is a heritable component to suicidal behaviour, encouraging the search for the associated risk alleles. Given the putative role of the 5-HT (5-hydroxytryptamine; serotonin) system in suicidal behaviour, serotonergic genes are leading candidates. In particular, several studies have reported an association with variants in the tryptophan hydroxylase (TPH) gene. Method. We studied six serotonergic gene polymorphisms in a well-characterized sample of 129 deliberate self-harm sub...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 116.2KB)
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- Publisher copy:
- 10.1017/S0033291703007463
-
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- Publisher:
- Cambridge University Press Publisher's website
- Journal:
- Psychological Medicine Journal website
- Volume:
- 33
- Issue:
- 5
- Pages:
- 775-783
- Publication date:
- 2003-07-05
- DOI:
- EISSN:
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1469-8978
- ISSN:
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0033-2917
- URN:
-
uuid:3ae3c858-17c7-433d-a7a3-012e6037a9e7
- Local pid:
- ora:1470
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Cambridge University Press
- Copyright date:
- 2003
- Notes:
- Citation: Pooley, E. C. et al. (2003). 'Deliberate self-harm is associated with allelic variation in the trytophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes', Psychological Medicine, 33(5), 775-783. [Available at http://journals.cambridge.org/action/displayJournal?jid=PSM].
Journal article
Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes
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Funding
American Foundation for Suicide Prevention
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Anglia and Oxford Research and Development Committee
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