- Abstract:
-
Definitive hematopoietic cells are generated de novo during ontogeny from a specialized subset of endothelium, the so-called hemogenic endothelium. In this review we give a brief overview of the identification of hemogenic endothelium, explore its links with the HSC lineage, and summarize recent insights into the nature of hemogenic endothelium and the microenvironmental and intrinsic regulators contributing to its transition into blood. Ultimately, a better understanding of the processes con...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.bcmd.2013.09.005
-
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- Journal:
- Blood cells, molecules and diseases
- Volume:
- 51
- Issue:
- 4
- Pages:
- 206-212
- Publication date:
- 2013-12-05
- DOI:
- EISSN:
-
1096-0961
- ISSN:
-
1079-9796
- URN:
-
uuid:3ac3341d-5333-4abd-8232-b969c998880c
- Source identifiers:
-
432283
- Local pid:
- pubs:432283
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
A short history of hemogenic endothelium.
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