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A short history of hemogenic endothelium.

Abstract:

Definitive hematopoietic cells are generated de novo during ontogeny from a specialized subset of endothelium, the so-called hemogenic endothelium. In this review we give a brief overview of the identification of hemogenic endothelium, explore its links with the HSC lineage, and summarize recent insights into the nature of hemogenic endothelium and the microenvironmental and intrinsic regulators contributing to its transition into blood. Ultimately, a better understanding of the processes con...

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Publication status:
Published

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Publisher copy:
10.1016/j.bcmd.2013.09.005

Authors


de Bruijn, MF More by this author
Journal:
Blood cells, molecules and diseases
Volume:
51
Issue:
4
Pages:
206-212
Publication date:
2013-12-05
DOI:
EISSN:
1096-0961
ISSN:
1079-9796
URN:
uuid:3ac3341d-5333-4abd-8232-b969c998880c
Source identifiers:
432283
Local pid:
pubs:432283

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