- Abstract:
-
Retinal stem cells have been isolated from the ciliary epithelium (CE) of the mammalian retina. However, the central neural retina (CNR) lacks the capability to regenerate, a phenomenon retained by lower vertebrates. Mutations in the Chx10 homeobox gene cause reduced proliferation of retinal progenitor cells during development, leading to microphthalmia. Recently, we showed that in Chx10(orJ/orJ) mice, dividing cells persist in the adult CNR, suggesting the existence of a dormant progenitor p...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.mcn.2008.03.008
-
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- Journal:
- Molecular and cellular neurosciences
- Volume:
- 38
- Issue:
- 3
- Pages:
- 359-373
- Publication date:
- 2008-07-05
- DOI:
- EISSN:
-
1095-9327
- ISSN:
-
1044-7431
- URN:
-
uuid:3ab5d81b-c91c-4062-8476-1840c4f5a910
- Source identifiers:
-
107254
- Local pid:
- pubs:107254
- Copyright date:
- 2008
Journal article
Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina.
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