A cognitive neuropsychological model of antidepressant drug action.

Journal article

The psychological mechanisms by which antidepressant drugs act to improve mood remain underspecified. In this paper we consider the evidence to suggest that early changes in emotional processing underlie subsequent mood improvement following antidepressant treatment. Negative biases in information processing are consistently found in depression, and we argue that primary mode of action of antidepressant drugs may be to remediate these biases providing a more positive social environment in whi...

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Authors: Pringle, A; Browning, M; Cowen, P; Harmer, C

• Publication status: Published
• Journal: Progress in neuro-psychopharmacology and biological psychiatry
• Volume: 35
• Issue: 7
• Pages: 1586-1592
• Publication date: 2011-08-01
• DOI: 10.1016/j.pnpbp.2010.07.022
• EISSN: 1878-4216
• ISSN: 0278-5846
• Language: English
• Keywords: Cognition; Models, Psychological; Time Factors; Antidepressive Agents; Humans; Depression; Depressive Disorder