Thesis
Asymmetric synthesis of α-alkylated aldehydes using chiral enamines
- Abstract:
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Direct generation of enantioenriched mono-α-alkylated aldehydes by intermolecular nucleophilic substitution is a general and long-standing problem in synthesis, and is of importance due to the diverse reactions such aldehydes undergo for introducing asymmetry into molecules.
The work described in this thesis initially details the development of the first lithium amide capable of efficiently converting terminal epoxide into enamine functionality, where the latter also demonstrates eff...
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Bibliographic Details
- Publication date:
- 2008
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3a90d43d-8124-41ba-8ece-be714bdefee0
- Local pid:
- ora:7485
- Deposit date:
- 2013-10-22
Terms of use
- Copyright holder:
- Naeem Kaka
- Copyright date:
- 2009
- Notes:
- This thesis is not currently available via ORA.
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