- Abstract:
-
UNLABELLED: We report significant and controlled cell death using novel x-ray-activatable titania nanoparticles (NPs) doped with lanthanides. Preferential incorporation of such materials into tumor tissue can enhance the effect of radiation therapy. Herein, the incorporation of gadolinium into the NPs is designed to optimize localized energy absorption from a conventional medical x-ray. This result is further optimized by the addition of other rare earth elements. Upon irradiation, energy is...
Expand abstract - Publisher copy:
- 10.1016/j.nano.2011.08.003
-
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- Journal:
- Nanomedicine : nanotechnology, biology, and medicine
- Volume:
- 8
- Issue:
- 4
- Pages:
- 526-536
- Publication date:
- 2012-05-05
- DOI:
- EISSN:
-
1549-9642
- ISSN:
-
1549-9634
- URN:
-
uuid:3a8f9357-8f87-48ec-8a56-0c5512c2d70d
- Source identifiers:
-
186510
- Local pid:
- pubs:186510
- Copyright date:
- 2012
Journal article
Nanoparticle augmented radiation treatment decreases cancer cell proliferation.
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