- Abstract:
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In many viral infections, a large number of different genetic variants can coexist within a host, leading to more virulent infections that are better able to evolve antiviral resistance and adapt to new hosts. But how is this diversity maintained? Why do faster-growing variants not outcompete slower-growing variants, and erode this diversity? One hypothesis is if there are mutually beneficial interactions between variants, with host cells infected by multiple different viral genomes producing...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 734.3kb)
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- Publisher copy:
- 10.1093/ve/vey028
-
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- Funding agency for:
- Leeks, A
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Virus Evolution Journal website
- Volume:
- 4
- Issue:
- 2
- Pages:
- Article: vey028
- Publication date:
- 2018-10-01
- Acceptance date:
- 2018-07-26
- DOI:
- ISSN:
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2057-1577
- Pubs id:
-
pubs:929816
- URN:
-
uri:3a8b7213-070f-4f28-8bd6-31e490541a13
- UUID:
-
uuid:3a8b7213-070f-4f28-8bd6-31e490541a13
- Local pid:
- pubs:929816
- Language:
- English
- Keywords:
- Copyright holder:
- Leeks et al.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 The Authors. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Beneficial coinfection can promote within-host viral diversity
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