Journal article
Association of ARNT splice variants with estrogen receptor-negative breast cancer, poor induction of vascular endothelial growth factor under hypoxia, and poor prognosis.
- Abstract:
-
The aryl hydrocarbon receptor nuclear translocator (ARNT) is a basic helix-loop-helix transcription factor that forms heterodimers with the aryl hydrocarbon receptor (AhR) or hypoxia inducible factor-1alpha to activate transcription via xenobiotic response element or hypoxia response element, respectively. Thus, it plays a major role in two key biochemical pathways involved in tumor growth. We previously showed that estrogen receptor (ER)-negative breast cancer cell lines expressed a splice v...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Volume:
- 7
- Issue:
- 4
- Pages:
- 818-823
- Publication date:
- 2001-04-05
- ISSN:
-
1078-0432
- URN:
-
uuid:3a7c0bfa-dd24-4a87-9558-4faff5418953
- Source identifiers:
-
114495
- Local pid:
- pubs:114495
Item Description
- Language:
- English
- Keywords:
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- Copyright date:
- 2001
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