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Identification of nine new susceptibility loci for endometrial cancer

Abstract:

Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we present an expanded meta-analysis of 12,906 endometrial cancer cases and 108,979 controls (including new genotype data for 5624 cases) and identify nine novel genome-wide significant loci, including a locus on 12q24.12 previously identified by meta-GWAS of...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-018-05427-7

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Role:
Author
ORCID:
0000-0002-5436-3232
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Role:
Author
ORCID:
0000-0002-2184-7708
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Role:
Author
ORCID:
0000-0001-8413-7669
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Grant:
K05 CA092002
P01 CA087969
P30 CA015083
P50 CA136393
R01 CA049449
R01 CA054281
R01 CA058598
R01 CA082838
R01 CA077398
R01 CA087538
R01 CA091019
R01 CA098346
R01 CA105212
R01 CA122443
R01 CA128978
R01 CA134958
R01 CA149429
R03 CA128008
R03 CA080636
R37 CA054281
U19 CA148065
U19 CA148112
U19 CA148537
UM1 CA186107
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Grant:
HHSN271201100004C
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Grant:
HHSN268201100002C
HHSN268201100003C
HHSN268201100004C
HHSN268201100001C
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Grant:
HHSN268201100001I
HHSN268201100002I
HHSN268201100004I
HHSN268201100046C
HHSN268201600001C
HHSN268201600002C
HHSN268201600003C
HHSN268201600004C
HHSN268201600018C
Publisher:
Nature Research
Journal:
Nature communications More from this journal
Volume:
9
Issue:
1
Article number:
3166
Publication date:
2018-08-09
Acceptance date:
2018-07-02
DOI:
ISSN:
2041-1723
Pmid:
30093612
Language:
English
Keywords:
Pubs id:
pubs:905623
UUID:
uuid:3a79438b-55b0-4ce4-9f77-fe7961554657
Local pid:
pubs:905623
Source identifiers:
905623
Deposit date:
2019-02-28

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