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Genome-wide association study of hepatitis C virus-and cryoglobulin-related vasculitis

Abstract:

The host genetic basis of mixed cryoglobulin vasculitis is not well understood and has not been studied in large cohorts. A genome-wide association study was conducted among 356 hepatitis C virus (HCV) RNA-positive individuals with cryoglobulin-related vasculitis and 447 ethnically matched, HCV RNA-positive controls. All cases had both serum cryoglobulins and a vasculitis syndrome. A total of 899 641 markers from the Illumina HumanOmni1-Quad chip were analyzed using logistic regression adjust...

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Publisher copy:
10.1038/gene.2014.41

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Publisher:
Nature Publishing Group
Journal:
Genes and Immunity
Volume:
15
Issue:
7
Pages:
500-505
Publication date:
2014-10-27
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:3a50a4f2-e863-455e-b7d4-edd800cb5e31
Source identifiers:
489844
Local pid:
pubs:489844
Language:
English

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