Journal article
The combination of tamoxifen with amphotericin B, but not with fluconazole, has synergistic activity against the majority of clinical isolates of Cryptococcus neoformans
- Abstract:
-
Background Cryptococcal meningitis has fatality rates of 40%‐70%, resulting in 200 000 deaths each year. The best outcomes are achieved with amphotericin combined with flucytosine but flucytosine is expensive and unavailable where most disease occurs. More effective and affordable treatments are needed. Tamoxifen, a selective oestrogen receptor modulator frequently indicated for breast cancer, has been found to have synergistic activity against the Cryptococcus neoform...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Mycoses Journal website
- Volume:
- 62
- Issue:
- 9
- Pages:
- 818-825
- Publication date:
- 2019-06-07
- Acceptance date:
- 2019-06-04
- DOI:
- EISSN:
-
1439-0507
- ISSN:
-
0933-7407
Item Description
- Keywords:
- Pubs id:
-
pubs:1009286
- UUID:
-
uuid:3a41f1cd-c7f8-4c9e-9caf-98b5d87c875a
- Local pid:
- pubs:1009286
- Source identifiers:
-
1009286
- Deposit date:
- 2019-06-07
Terms of use
- Copyright holder:
- Hai et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors. Mycoses published by Blackwell Verlag GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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