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Journal article

Modulation of osteoclastogenesis by fatty acids.

Abstract:

Clinical studies have shown that total body fat mass is related to both bone density and fracture risk and that fat ingestion reduces bone turnover. These effects are at least partially mediated by endocrine mechanisms, but it is possible that lipids might act directly on bone. We assessed the effects of broad fractions of milk lipids in osteoblasts, bone marrow, and neonatal mouse calvariae. Several milk fractions and their hydrolysates inhibited osteoclastogenesis in bone marrow cultures, s...

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Publication status:
Published

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Publisher copy:
10.1210/en.2008-0111

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Journal:
Endocrinology
Volume:
149
Issue:
11
Pages:
5688-5695
Publication date:
2008-11-05
DOI:
EISSN:
1945-7170
ISSN:
0013-7227
URN:
uuid:3a2541db-0bf6-4ffc-a527-cf105b4d2027
Source identifiers:
108054
Local pid:
pubs:108054

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