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Journal article

Dangerous liaisons at the virological synapse.

Abstract:
Cell-to-cell viral transmission facilitates the propagation of HIV-1 and human T cell leukemia virus type 1. Mechanisms of cell-to-cell transmission by retroviruses were not well understood until the recent description of virological synapses (VSs). VSs function as specialized sites of immune cell-to-cell contact that direct virus infection. Deciphering the molecular mechanisms of VS formation provides a fascinating insight into how pathogens subvert immune cell communication programs and achieve viral spread.

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Publisher copy:
10.1172/jci22812

Authors


Sattentau, Q More by this author
Journal:
The Journal of clinical investigation
Volume:
114
Issue:
5
Pages:
605-610
Publication date:
2004-09-05
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
URN:
uuid:3a0b3858-3e6b-43f5-8765-e6510ed17dba
Source identifiers:
23263
Local pid:
pubs:23263

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