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Journal article

Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2

Abstract:

Background: In falciparum malaria sequestration of erythrocytes containing mature forms of Plasmodium falciparum in the microvasculature of vital organs is central to pathology, but quantitation of this hidden sequestered parasite load in vivo has not previously been possible. The peripheral blood parasite count measures only the circulating, relatively non-pathogenic parasite numbers. P. falciparum releases a specific histidine-rich protein (PfHRP2) into plasma. Quantitative measurement of p...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.0020204

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
2
Issue:
8
Article number:
0788-0797
Publication date:
2005-01-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
UUID:
uuid:39f4ffdc-715b-4f0e-9244-a9aabb00eae7
Local pid:
pubs:95516
Source identifiers:
95516
Deposit date:
2012-12-19

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