Risk of nephropathy can be detected before the onset of microalbuminuria during the early years after diagnosis of type 1 diabetes.

Journal article

OBJECTIVE: The early detection of a rise in albumin excretion within the normal range could permit early intervention to prevent the development of microalbuminuria (MA) in genetically susceptible subjects with type 1 diabetes. In the Oxford Regional Prospective Study we prospectively examined urine albumin excretion during the first years after diagnosis of childhood type 1 diabetes. RESEARCH DESIGN AND METHODS: Between 1986 and 1995, 511 subjects aged < 16 years were recruited at diagno...

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Authors: Schultz, C; Neil, H; Dalton, R; Dunger, D

• Journal: Diabetes care
• Volume: 23
• Issue: 12
• Pages: 1811-1815
• Publication date: 2000-12-01
• DOI: 10.2337/diacare.23.12.1811
• EISSN: 1935-5548
• ISSN: 0149-5992
• Language: English
• Keywords: Albuminuria; Diabetes Mellitus, Type 1; Child; Adolescent; Child, Preschool; Puberty; Risk Factors; Albumins; Male; Female; Creatinine; Time Factors; Infant; Oxforn Regional Prospective Study Group; Prospective Studies; Diabetic Nephropathies; Humans; Genetic Predisposition to Disease; Hemoglobin A, Glycosylated