- Abstract:
-
Vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor 2 (VEGFR2) are the key factors mediating neo-vascularization. They are often coexpressed in breast cancer. Sex steroids may stimulate angiogenesis via the estrogen receptor (ER) pathway. We investigated to compare the effects of the addition of tamoxifen to epirubicin versus epirubicin alone on VEGF and VEGFR2 expression in breast cancer patients. The expression of VEGF and VEGFR2 was assessed on tis...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s10549-010-1063-0
-
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- Journal:
- Breast cancer research and treatment
- Volume:
- 123
- Issue:
- 3
- Pages:
- 795-804
- Publication date:
- 2010-10-05
- DOI:
- EISSN:
-
1573-7217
- ISSN:
-
0167-6806
- URN:
-
uuid:39f399df-56e5-4c2c-862c-83c9a77aac8e
- Source identifiers:
-
125067
- Local pid:
- pubs:125067
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Anti-angiogenic effect of tamoxifen combined with epirubicin in breast cancer patients.
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