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Journal article

Progressive changes in T-1, T-2 and left-ventricular histo-architecture in the fixed and embedded rat heart

Abstract:

Chemical tissue fixation, followed by embedding in either agarose or Fomblin, is common practice in time-intensive MRI studies of ex vivo biological samples, and is required to prevent tissue autolysis and sample motion. However, the combined effect of fixation and sample embedding may alter tissue structure and MRI properties. We investigated the progressive changes in T 1 and T 2 relaxation times, and the arrangement of locally prevailing cardiomyocyte orientation determined using diffusion...

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Publication status:
Published

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Publisher copy:
10.1002/nbm.1629

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Journal:
NMR IN BIOMEDICINE
Volume:
24
Issue:
7
Pages:
836-843
Publication date:
2011-08-05
DOI:
EISSN:
1099-1492
ISSN:
0952-3480
URN:
uuid:39eca379-dac2-4a56-ad47-2b0804faefc6
Source identifiers:
177349
Local pid:
pubs:177349

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