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Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria.

Abstract:

Ribosomes are universal translators of the genetic code into protein and represent macromolecular structures that are asymmetric, often heterogeneous, and contain dynamic regions. These properties pose considerable challenges for modern-day structural biology. Despite these obstacles, high-resolution x-ray structures of the 30S and 50S subunits have revealed the RNA architecture and its interactions with proteins for ribosomes from Thermus thermophilus, Deinococcus radiodurans, and Haloarcula...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0502193102

Authors


Videler, H More by this author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
102
Issue:
23
Pages:
8192-8197
Publication date:
2005-06-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:39e2799e-a4c9-437b-889a-faaf9329adae
Source identifiers:
59274
Local pid:
pubs:59274

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