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Red cell selectivity in malaria: a study of multiple-infected erythrocytes.

Abstract:

To characterize red cell susceptibility to invasion in malaria, a selectivity index (SI) was calculated as the ratio of observed number of multiple-infected red cells to that expected from a random process (Poisson distribution). In patients with falciparum malaria (n = 100) SI decreased with increasing parasitaemia (P < 0.001), and correlated inversely with plasma lactate concentrations, chosen prospectively as a measure of disease severity (r = -0.36, P < 0.001). For parasitaemias <...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
93
Issue:
2
Pages:
165-168
Publication date:
1999-01-01
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:39e08ab6-1ae0-4637-acd6-5306061b946e
Source identifiers:
36982
Local pid:
pubs:36982

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