Journal article
Involvement of the 4-1BB/4-1BBL pathway in control of monocyte numbers by invariant NKT cells.
- Abstract:
-
4-1BB is expressed on invariant (i)NKT cells, but its role is unclear. We showed previously that iNKT cells are involved in control of monocyte numbers during influenza A virus (IAV) infection and now question the role of the 4-1BB costimulatory pathway in the cross-talk between these cells. We found that iNKT cells and monocytes interact to promote expression of 4-1BB and 4-1BBL, respectively. Blockade of 4-1BB/L pathway under resting coculture conditions increased apoptosis of iNKT cells an...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.1302385
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Authors
Bibliographic Details
- Publisher:
- American Association of Immunologists
- Journal:
- Journal of Immunology
- Volume:
- 192
- Issue:
- 8
- Pages:
- 3898-3907
- Publication date:
- 2014-04-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
457837
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:457837
- UUID:
-
uuid:39d05014-7301-4087-9199-1fc73b63ab49
- Local pid:
- pubs:457837
- Deposit date:
- 2014-05-10
Terms of use
- Copyright date:
- 2014
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