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Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus.

Abstract:

Barrett's esophagus is an example of a pre-invasive state, for which current endoscopic surveillance methods to detect dysplasia are time consuming and inadequate. The prognosis of cancer arising in Barrett's esophagus is improved by early detection at the stage of mucosal carcinoma or high-grade dysplasia. Molecular imaging methods could revolutionize the detection of dysplasia, provided they permit a wide field of view and highlight abnormalities in real time. We show here that cell-surface...

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Publisher copy:
10.1038/nm.2616

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
Role:
Author
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Journal:
Nature medicine
Volume:
18
Issue:
2
Pages:
315-321
Publication date:
2012-02-05
DOI:
EISSN:
1546-170X
ISSN:
1078-8956
URN:
uuid:39baf80e-205b-4862-98cf-e965c17090d4
Source identifiers:
472426
Local pid:
pubs:472426

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