An epicardial floor plan for building and rebuilding the mammalian heart.

Journal article

The epicardium is a mesothelial cell layer which contributes to the coronary vessels and myocardium and acts as an important source of trophic signals to maintain continued growth and differentiation of the developing heart. The precise lineage potential of the embryonic epicardium has come under recent scrutiny with notable questions around its capacity to give rise to derivative vascular endothelial cells and cardiomyocytes. The importance of the epicardium is not restricted to heart format...

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Authors: Riley, P

• Publication status: Published
• Journal: Current topics in developmental biology
• Volume: 100
• Pages: 233-251
• Publication date: 2012-01-01
• DOI: 10.1016/b978-0-12-387786-4.00007-5
• EISSN: 1557-8933
• ISSN: 0070-2153
• Language: English
• Keywords: Animals; Cell Differentiation; Heart; Humans; Myocardium; Homeostasis; Cell Lineage; Signal Transduction