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Thesis

Signal processing methods for characterisation of ventricular repolarisation using the surface electrocardiogram

Abstract:

This thesis investigates the mechanisms underlying drug-induced arrhythmia and pro- poses a new approach for the automated analysis of the electrocardiogram (ECG). The current method of assessing the cardiac safety of new drugs in clinical trials is by the measurement and analysis of the QT interval. However, the sensitivity and specificity of the QT interval has been questioned and alternative biomarkers based on T-wave mor- phology have been proposed in the literature. The mechanisms und...

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Research group:
Biomedical Signal Processing & e-health
Oxford college:
Keble College
Role:
Author
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Division:
MPLS
Department:
Engineering Science
Role:
Author

Contributors

Division:
MPLS
Department:
Engineering Science
Role:
Supervisor
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Funding agency for:
Brennan, T
Publication date:
2009
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:39ae285a-b8dd-4aae-b60e-36f95fb84f37
Local pid:
ora:5406
Deposit date:
2011-06-03

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