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Linear IgA disease: cylindroma demonstrates heterogeneity of the target antigens.

Abstract:

Serum from 58 patients with linear IgA disease was tested by indirect immunofluorescence on the novel substrate cylindroma, which produces an abundance of basement membrane components. The use of split skin and of cylindroma has identified 2 target antigens. The majority of patients have a target antigen associated with epidermal cells and similar in distribution on cylindroma to hemidesmosome proteins. A minority have a dermal antigen with the distribution of collagen VII on cylindroma. Thes...

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Publication status:
Published

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Publisher copy:
10.1159/000246944

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Volume:
189 Suppl 1
Issue:
SUPPL. 1
Pages:
102-104
Host title:
Dermatology (Basel, Switzerland)
Publication date:
1994-01-01
Event location:
SWITZERLAND
DOI:
EISSN:
1421-9832
ISSN:
1018-8665
Source identifiers:
8400

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