Journal article
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing.
- Abstract:
-
Malaria elimination strategies require surveillance of the parasite population for genetic changes that demand a public health response, such as new forms of drug resistance. Here we describe methods for the large-scale analysis of genetic variation in Plasmodium falciparum by deep sequencing of parasite DNA obtained from the blood of patients with malaria, either directly or after short-term culture. Analysis of 86,158 exonic single nucleotide polymorphisms that passed genotyping quality con...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/nature11174
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Authors
Bibliographic Details
- Journal:
- Nature
- Volume:
- 487
- Issue:
- 7407
- Pages:
- 375-379
- Publication date:
- 2012-07-01
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
- Source identifiers:
-
323975
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:323975
- UUID:
-
uuid:398b526d-1ff9-4b93-95a4-caea3a746679
- Local pid:
- pubs:323975
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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