Journal article
Hepatitis B small surface antigen particles are octahedral.
- Abstract:
-
The infectious component of hepatitis B (HB) virus (HBV), the Dane particle, has a diameter of approximately 44 nm and consists of a double-layered capsid particle enclosing a circular, incomplete double-stranded DNA genome. The outer capsid layer is formed from the HB surface antigen (HBsAg) and lipid, whereas the inner layer is formed from the HB core Ag assembled into an icosahedral structure. During chronic infection HBsAg is expressed in large excess as noninfectious quasispherical parti...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 102
- Issue:
- 41
- Pages:
- 14783-14788
- Publication date:
- 2005-10-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:24526
- UUID:
-
uuid:39854ce5-15d8-42ad-a80f-82aef8515d6c
- Local pid:
- pubs:24526
- Source identifiers:
-
24526
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2005
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