Journal article icon

Journal article

Site of carotid plaque ulceration in relation to direction of blood flow: an angiographic and pathological study.

Abstract:

BACKGROUND: Rupture of atherosclerotic plaque is the main cause of acute coronary syndromes and carotid territory ischaemic stroke. Haemodynamic stress is important in early plaque formation and may affect the stability of mature plaques. There is some evidence that macrophage infiltration and plaque rupture tend to localise to the proximal (upstream) part of the plaque where shear stress is highest. However, previous studies have been too small to assess this reliably. We studied the site o...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1159/000072559

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
Journal:
Cerebrovascular diseases (Basel, Switzerland)
Volume:
16
Issue:
4
Pages:
369-375
Publication date:
2003-01-01
DOI:
EISSN:
1421-9786
ISSN:
1015-9770
URN:
uuid:397dfacc-4a50-42d8-a780-a03e71fac6d9
Source identifiers:
119416
Local pid:
pubs:119416

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP