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Journal article

HLA-DR and DQ polymorphisms in bullous pemphigoid from northern China.

Abstract:

Bullous pemphigoid (BP) is an autoimmune disease mediated by autoantibodies against hemidesmosome components. This study used PCR-sequence-specific primers to genotype polymorphisms in HLA-DR and DQ in 25 BP patients and 57 normal controls from northern China. We found lower frequencies of DRB1*08 (DR8) and DRB1*08/DQB1*06 (DR8/DQ6) haplotypes in BP patients than in controls (4.08% vs. 15.19% and 1.54% vs. 13.82%, respectively; P < 0.05), suggesting a protective role for DR8 and DR8/DQ6 ha...

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Publication status:
Published

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Authors


Barnardo, M More by this author
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Journal:
Clinical and experimental dermatology
Volume:
27
Issue:
4
Pages:
319-321
Publication date:
2002-06-05
DOI:
EISSN:
1365-2230
ISSN:
0307-6938
URN:
uuid:3978a4ed-6714-4d08-8501-2e8b9b5c2cf4
Source identifiers:
7185
Local pid:
pubs:7185

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