- Abstract:
-
Bullous pemphigoid (BP) is an autoimmune disease mediated by autoantibodies against hemidesmosome components. This study used PCR-sequence-specific primers to genotype polymorphisms in HLA-DR and DQ in 25 BP patients and 57 normal controls from northern China. We found lower frequencies of DRB1*08 (DR8) and DRB1*08/DQB1*06 (DR8/DQ6) haplotypes in BP patients than in controls (4.08% vs. 15.19% and 1.54% vs. 13.82%, respectively; P < 0.05), suggesting a protective role for DR8 and DR8/DQ6 ha...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1046/j.1365-2230.2002.01037.x
-
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- Journal:
- Clinical and experimental dermatology
- Volume:
- 27
- Issue:
- 4
- Pages:
- 319-321
- Publication date:
- 2002-06-05
- DOI:
- EISSN:
-
1365-2230
- ISSN:
-
0307-6938
- URN:
-
uuid:3978a4ed-6714-4d08-8501-2e8b9b5c2cf4
- Source identifiers:
-
7185
- Local pid:
- pubs:7185
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
HLA-DR and DQ polymorphisms in bullous pemphigoid from northern China.
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