Journal article
DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence.
- Abstract:
-
The lactose repressor protein may bind DNA in two possible configurations: a specific one, if the DNA sequence corresponds to a binding site, and a non-specific one otherwise. To find its target sequences, the lactose repressor first binds non-specifically to DNA, and subsequently, it rapidly searches for a binding site. Atomic structures of non-specific and specific complexes are available from crystallographic and nuclear magnetic resonance experiments. However, what remains unknown is a de...
Expand abstract
- Publication status:
- Published
Actions
Access Document
- Publisher copy:
- 10.1093/nar/gkt099
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Bibliographic Details
- Journal:
- Nucleic acids research
- Volume:
- 41
- Issue:
- 7
- Pages:
- 3963-3972
- Publication date:
- 2013-04-01
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- Source identifiers:
-
387133
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:387133
- UUID:
-
uuid:394c43c4-a8f7-42ec-a6c5-ff12c49ff9b1
- Local pid:
- pubs:387133
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2013
If you are the owner of this record, you can report an update to it here: Report update to this record