- Abstract:
-
Inward rectifier (Kir) potassium channels contribute to the control of electrical activity in excitable tissues and their activity is modulated by many biochemical factors, including protons. Heteromeric Kir4.1-Kir5.1 channels are highly pH sensitive within the physiological range of pH changes and are strongly expressed by the peripheral chemosensors as well as in the brainstem pH-sensitive areas which mediate respiratory responses to changes in blood and brain levels of P(CO(2))/[H(+)]. In ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1113/expphysiol.2010.055848
-
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- Journal:
- Experimental physiology
- Volume:
- 96
- Issue:
- 4
- Pages:
- 451-459
- Publication date:
- 2011-04-05
- DOI:
- EISSN:
-
1469-445X
- ISSN:
-
0958-0670
- URN:
-
uuid:39356e54-a8b2-417e-9402-050e92c35bcc
- Source identifiers:
-
127350
- Local pid:
- pubs:127350
- Copyright date:
- 2011
Journal article
Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16).
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