Obesity and polycystic ovary syndrome.

Journal article

The aetiology of Polycystic Ovary Syndrome (PCOS) is complex and multifactorial. There is much evidence, however, to suggest that adipose tissue plays an important role in the development and maintenance of PCOS pathology. There is a close correlation between adiposity and symptom severity in women with PCOS, and even modest reductions in weight generally translate into significant improvements in menstrual regularity, fertility and hyperandrogenic features. This review article considers the ...

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Authors: Barber, T; McCarthy, M; Wass, J; Franks, S

• Publication status: Published
• Journal: Clinical endocrinology
• Volume: 65
• Issue: 2
• Pages: 137-145
• Publication date: 2006-08-01
• DOI: 10.1111/j.1365-2265.2006.02587.x
• EISSN: 1365-2265
• ISSN: 0300-0664
• Language: English
• Keywords: Cytokines; Adipocytes; Insulin Resistance; Humans; Estrogens; Obesity; Appetite Regulation; Female; Polycystic Ovary Syndrome; Lipid Metabolism; Androgens; Adult