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Dissecting early regulatory relationships in the lamprey neural crest gene network.

Abstract:

The neural crest, a multipotent embryonic cell type, originates at the border between neural and nonneural ectoderm. After neural tube closure, these cells undergo an epithelial-mesenchymal transition, migrate to precise, often distant locations, and differentiate into diverse derivatives. Analyses of expression and function of signaling and transcription factors in higher vertebrates has led to the proposal that a neural crest gene regulatory network (NC-GRN) orchestrates neural crest format...

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Publisher copy:
10.1073/pnas.0806009105

Authors


Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
105
Issue:
51
Pages:
20083-20088
Publication date:
2008-12-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Source identifiers:
271451
Language:
English
Keywords:
Pubs id:
pubs:271451
UUID:
uuid:39294bd4-2d4a-4266-8e2d-3790248249bd
Local pid:
pubs:271451
Deposit date:
2012-12-19

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