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Epidermal growth factor receptor expression in anal canal carcinoma.

Abstract:

Most anal canal carcinomas (ACCs) are squamous cell carcinomas (SCCs). SCCs in other tumor sites strongly express epidermal growth factor receptors (EGFRs), the inhibition of which might result in favorable changes in tumor growth. A review of the published scientific literature reveals no information regarding the expression of EGFR in ACCs. Therefore, we obtained archived pathology samples from ACC biopsies and examined the frequency and level of expression of EGFR and other cell surface an...

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Publication status:
Published

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Publisher copy:
10.1309/X4UADHVN317V2XMW

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences, Biomedical Research Centre
Role:
Author
Journal:
American journal of clinical pathology
Volume:
124
Issue:
1
Pages:
20-23
Publication date:
2005-07-05
DOI:
EISSN:
1943-7722
ISSN:
0002-9173
URN:
uuid:3914a71a-8711-49ee-bbac-0473d03cad3d
Source identifiers:
121996
Local pid:
pubs:121996

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