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Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations

Abstract:

Background and Purpose: The contribution of genetics to stroke risk, and whether this differs for different stroke subtypes, remains uncertain. Genomewide complex trait analysis allows heritability to be assessed from genomewide association study (GWAS) data. Previous candidate gene studies have identified many associations with stoke but whether these are important requires replication in large independent data sets. GWAS data sets provide a powerful resource to perform replication studies. ...

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Publisher copy:
10.1161/STROKEAHA.112.665760

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Journal:
Stroke More from this journal
Volume:
43
Issue:
12
Pages:
3161-3167
Publication date:
2012-12-01
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Pubs id:
pubs:368206
UUID:
uuid:391006d0-f3b4-4f12-b0b9-709e38c412cb
Local pid:
pubs:368206
Source identifiers:
368206
Deposit date:
2013-11-17

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