Journal article
Lipid-based passivation in nanofluidics.
- Abstract:
-
Stretching DNA in nanochannels is a useful tool for direct, visual studies of genomic DNA at the single molecule level. To facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We demonstrate virtually complete long-term passivation of nanochannel surfaces to a range of relevant reagents, including streptavidin-coated quantum dots, RecA proteins, and RecA-DNA complexes. We show th...
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- Publication status:
- Published
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- Publisher copy:
- 10.1021/nl204535h
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Authors
Bibliographic Details
- Journal:
- Nano letters
- Volume:
- 12
- Issue:
- 5
- Pages:
- 2260-2265
- Publication date:
- 2012-05-01
- DOI:
- EISSN:
-
1530-6992
- ISSN:
-
1530-6984
- Source identifiers:
-
320343
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:320343
- UUID:
-
uuid:38e97366-4e0c-436a-9a68-ea3f16f19e69
- Local pid:
- pubs:320343
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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