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Journal article

Brain metabolism is abnormal in the mdx model of Duchenne muscular dystrophy.

Abstract:

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder primarily affecting young boys, often causing mental retardation in addition to the well-known progressive muscular weakness. Normal dystrophin expression is lacking in skeletal muscle and the CNS of both DMD children and the mdx mouse model. To date, 31P-magnetic resonance spectroscopy (MRS) has shown in vivo several abnormalities within skeletal muscle of mdx mice and DMD boys. In this study, we determined whether similar abn...

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Publication status:
Published

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Publisher copy:
10.1093/brain/119.3.1039

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Brain : a journal of neurology
Volume:
119 ( Pt 3)
Issue:
3
Pages:
1039-1044
Publication date:
1996-06-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:38e79311-1bda-451d-898e-b2b2789abc97
Source identifiers:
376239
Local pid:
pubs:376239

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