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Placebo for depression: we need to improve the quality of scientific information but also reject too simplistic approaches or ideological nihilism.

Abstract:

The placebo response plays a major role in psychiatry, particularly in depression. A new network meta-analysis investigates whether the effects of placebo vary in studies comparing fluoxetine and venlafaxine, two widely prescribed antidepressants. Even though data from this article indicate that the effects of placebos do not differ, publication bias cannot be ruled out. The authors use their finding to criticise the paradigm of evidence-based medicine, questioning whether there is anything c...

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Publication status:
Published
Peer review status:
Not peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1741-7015-12-105

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
National Institute for Health Research More from this funder
Publisher:
BioMed Central Ltd.
Journal:
BMC medicine Journal website
Volume:
12
Issue:
1
Pages:
105
Publication date:
2014-06-25
DOI:
EISSN:
1741-7015
ISSN:
1741-7015
URN:
uuid:38de353b-f0ea-4a61-af72-14f92668081a
Source identifiers:
471170
Local pid:
pubs:471170

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