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Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review.

Abstract:

INTRODUCTION: Induction of an inflammatory response is thought to have a significant role in the complications that follow cardiopulmonary bypass (CPB). The statin drugs are increasingly being recognized as having potent anti-inflammatory effects and hence have potential to influence an important mechanism of injury in CPB, although there is no current confirmation that this is indeed the case. Our objective was to systematically review if pre-operative prophylactic statin therapy, compared ...

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Publication status:
Published

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Publisher copy:
10.1186/cc8135

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences
Role:
Author
Journal:
Critical care (London, England)
Volume:
13
Issue:
5
Pages:
R165
Publication date:
2009-01-01
DOI:
EISSN:
1466-609X
ISSN:
1364-8535
URN:
uuid:38d026b8-90d6-418e-9c6b-2769f6a39cea
Source identifiers:
244257
Local pid:
pubs:244257

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