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Journal article

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

Abstract:

Neutralizing antibodies (NAb) able to react to heterologous viruses are generated during natural HIV-1 infection in some individuals. Further knowledge is required in order to understand the factors contributing to induction of cross-reactive NAb responses. Here a well-established model of experimental pathogenic infection in cynomolgus macaques, which reproduces long-lasting HIV-1 infection, was used to study the NAb response as well as the viral evolution of the highly neutralization-resist...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1001084

Authors


Ozkaya Sahin, G More by this author
More by this author
Institution:
University of Oxford
More by this author
Institution:
University of Oxford
Uchtenhagen, H More by this author
Sheik-Khalil, E More by this author
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European Union More from this funder
Swedish International Development Cooperation Agency More from this funder
Swedish Research Council More from this funder
The Scientific and Technological Research Council of Turkey More from this funder
Medical Research Council More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
6
Issue:
9
Pages:
e1001084
Publication date:
2010
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:38c2a04f-ab0b-4786-a224-04ee69296646
Source identifiers:
112453
Local pid:
pubs:112453

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