Journal article
Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.
- Abstract:
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Neutralizing antibodies (NAb) able to react to heterologous viruses are generated during natural HIV-1 infection in some individuals. Further knowledge is required in order to understand the factors contributing to induction of cross-reactive NAb responses. Here a well-established model of experimental pathogenic infection in cynomolgus macaques, which reproduces long-lasting HIV-1 infection, was used to study the NAb response as well as the viral evolution of the highly neutralization-resist...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.4MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.ppat.1001084
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Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS pathogens More from this journal
- Volume:
- 6
- Issue:
- 9
- Pages:
- e1001084
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1553-7374
- ISSN:
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1553-7366
Item Description
- Language:
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English
- Keywords:
-
- UUID:
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uuid:38c2a04f-ab0b-4786-a224-04ee69296646
- Local pid:
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pubs:112453
- Source identifiers:
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112453
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Özkaya Şahin et al
- Copyright date:
- 2010
- Notes:
- © 2010 Özkaya Şahin et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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