Journal article icon

Journal article

In vitro kinetic studies on the mechanism of oxygen-dependent cellular uptake of copper radiopharmaceuticals.

Abstract:

The development of hypoxia-selective radiopharmaceuticals for use as therapeutic and/or imaging agents is of vital importance for both early identification and treatment of cancer and in the design of new drugs. Radiotracers based on copper for use in positron emission tomography have received great attention due to the successful application of copper(II) bis(thiosemicarbazonato) complexes, such as [(60/62/64)Cu(II)ATSM] and [(60/62/64)Cu(II)PTSM], as markers for tumour hypoxia and blood per...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1088/0031-9155/54/7/017

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
Journal:
Physics in medicine and biology
Volume:
54
Issue:
7
Pages:
2103-2119
Publication date:
2009-04-01
DOI:
EISSN:
1361-6560
ISSN:
0031-9155
Source identifiers:
20644
Language:
English
Keywords:
Pubs id:
pubs:20644
UUID:
uuid:38a79622-6e96-4100-85c5-765bf2b3b8ee
Local pid:
pubs:20644
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP