Journal article
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection.
- Abstract:
-
BACKGROUND and AIMS: Cytotoxic T cells have been suggested to be responsible for lysis of hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency, kinetics, phenotype, and capacity for clonal expansion of circulating HBV-specific CD8 cells were analyzed directly in patients with acute HBV infection to clarify their pathogenetic role. METHODS: Three HLA-A2 peptide tetramers able to visualize HBV core, envelope, and polymerase epitope-specific cytotoxic T lymp...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0016-5085(99)70289-1
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Bibliographic Details
- Journal:
- Gastroenterology
- Volume:
- 117
- Issue:
- 6
- Pages:
- 1386-1396
- Publication date:
- 1999-12-01
- DOI:
- EISSN:
-
1528-0012
- ISSN:
-
0016-5085
- Source identifiers:
-
13712
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:13712
- UUID:
-
uuid:38a190a6-f80d-4716-9fa1-6ac169a00e43
- Local pid:
- pubs:13712
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1999
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