Journal article
Design principles of biochemical oscillators.
- Abstract:
-
Cellular rhythms are generated by complex interactions among genes, proteins and metabolites. They are used to control every aspect of cell physiology, from signalling, motility and development to growth, division and death. We consider specific examples of oscillatory processes and discuss four general requirements for biochemical oscillations: negative feedback, time delay, sufficient 'nonlinearity' of the reaction kinetics and proper balancing of the timescales of opposing chemical reactio...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/nrm2530
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Bibliographic Details
- Journal:
- Nature reviews. Molecular cell biology
- Volume:
- 9
- Issue:
- 12
- Pages:
- 981-991
- Publication date:
- 2008-12-01
- DOI:
- EISSN:
-
1471-0080
- ISSN:
-
1471-0072
- Source identifiers:
-
99787
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:99787
- UUID:
-
uuid:388a8d40-b451-42b5-84f3-5679897dd51f
- Local pid:
- pubs:99787
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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