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Methadone dose and neonatal abstinence syndrome-systematic review and meta-analysis.

Abstract:

AIM: To determine if there is a relationship between maternal methadone dose in pregnancy and the diagnosis or medical treatment of neonatal abstinence syndrome (NAS). METHODS: PubMed, EMBASE, the Cochrane Library and PsychINFO were searched for studies reporting on methadone use in pregnancy and NAS (1966-2009). The relative risk (RR) of NAS was compared for methadone doses above versus below a range of cut-off points. Summary RRs and 95% confidence intervals (CI) were estimated using rando...

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Publication status:
Published

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Authors


Cleary, BJ More by this author
Donnelly, J More by this author
Strawbridge, J More by this author
Gallagher, PJ More by this author
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Journal:
Addiction (Abingdon, England)
Volume:
105
Issue:
12
Pages:
2071-2084
Publication date:
2010-12-05
DOI:
EISSN:
1360-0443
ISSN:
0965-2140
URN:
uuid:388a88a5-a5ee-4858-b55d-95e7c1258667
Source identifiers:
79133
Local pid:
pubs:79133

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